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Fig. 2. Progression of fibronectin (FN) fibril formation. CHO{alpha}5 cells were incubated with rat plasma FN (25 µg ml–1) for 1 hour or 8 hours. Matrix was visualized by staining with IC3 anti-rat FN antibody followed by fluorescein-labeled secondary antibody. FN fibrils accumulate over time to form a dense network around the cells.