Fig. 10. Dynamic behavior of the Nuf2-Hec1 complex during the cell cycle.
Illustration of the dynamic behavior of the Nuf2-Hec1 complex during the cell
cycle. Association of the Nuf2-Hec1 complex with centrosomes is dynamic during
G1 and S phases. The complex moves through the nuclear membrane to centromeres
during G2 and mitosis. Association of the complex with centromeres is stable.
In the centromere, the complex provides a place for the Mad2 complex to attach
to the kinetochore.