Fig. 1. MTOC targeting of incoming HFV in the early step of infection. Five hours after infection, numerous free incoming viral capsids are detected around the centrosome at a low (top) and a high (bottom) m.o.i. by electron microscopy. Viral capsids in close vicinity to microtubules are easily observed in the higher resolution picture of the centrosomal region. Scale bar, 450 nm (upper and lower insets). N, nucleus.