Fig. 8. Left panel: Immunostaining of Cx31 expression in tail epidermis on days 1-5 after wound healing. Cx31 protein amount decreased during the first 2 days postwounding and Cx31 protein was mainly localized in the basal layer. On days 4 and 5, the expression level increased again to the level of uninjured epidermis. Right panel: Cx31 expression in tail epidermis of mice with decreased amount of Cx43 protein (Cx43^CreER(T)/fl, induced). Maximal Cx31 expression after wounding occurred one day earlier than in wild-type epidermis. Nuclei were stained with Hoechst 33258 fluorescent dye. Basal lamina is marked by white dots. Bars, 25 µm. Coa, coagulum.