Fig. 6. Role of the cytoskeleton in cell-cell contact-mediated proliferation.
Immunofluorescence images of actin (left) or ß-catenin (right) staining
and graphs of percentage of cells in S phase on agarose patterns treated with
cytochalasin D (A-B) or latrunculin B (C-D) to disrupt the actin cytoskeleton
and BDM (E-F) or ML-7 (G-H) to inhibit actomyosin dynamics. Broken lines
(white) indicate the borders of the wells. Scale bar: 25 µm. Actin and
ß-catenin images were acquired on different samples. Error bars indicate
s.d. of three experiments, with (*) P<0.05 relative to
untreated controls, as calculated by Student's t-test.