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Fig. 2. Ser10 phosphorylation during cell cycle progression. Chromatin containing histone H3 phosphorylated at Ser10 is indicated in red, chromatin containing unphosphorylated Ser10 is grey, centrosomes are blue and microtubules green. Ser10 phosphorylation begins in G2 at pericentromeric chromatin, is complete in prophase and decreases upon exit from mitosis.