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Fig. 6. Depletion of PAT-2/{alpha} or PAT-3/ß integrins disrupts muscle structure. Rhodamine-conjugated phalloidin was used to stain actin filaments in body wall muscle cells of animals grown on bacteria carrying the empty vector (A), or bacteria expressing dsRNA for talin (B), pat-2 (C) and pat-3 (D) for 72 hours. Compared with wild type, actin filaments were disorganized in all of the RNAi-treated animals. Percentages in each panel represent proportion of paralyzed animals at 72 hours post-hatch (±s.d.). Scale bars: 25 µm.