Fig. 1. Schematic representation of irradiation regimes. Female host mdx mice were subjected to one of the following regimes: no treatment (control, white mouse), whole body irradiation (WBI, black mouse) (A), WBI plus bone marrow reconstitution (BMR speckled mouse) (B), WBI with single leg excluded (white leg and black body) (C), single leg irradiation (black leg) (D), or NK cell depletion followed by single leg irradiation (NK- and black leg) (E). Myoblast transfer therapy (MTT) was performed 1 hour, 24 hours or 1 week after irradiation, and samples taken up to 24 weeks after injection of cultured donor male myoblasts.