Fig. 2. (A) Number of donor male myoblasts after MTT of untreated (control), whole body irradiated (WBI) and WBI followed 1 hour later by bone marrow reconstitution (BMR) hosts. All mdx host mice are female. MTT was performed 24 hours after WBI and muscles sampled at 1, 24 and 72 hours. Schematics of the irradiation treatment of host mice as described in Fig. 1 are indicated in the top right-hand corner. Bars indicate standard deviation. *P<0.05 and **P<0.005 (untreated to treated samples) using ANOVA; d and dd indicates significance of P<0.05 or P<0.005, respectively, between treatment groups at each time point using ANOVA; n=6 unless otherwise stated. (B) Number of donor male myoblasts after MTT of untreated (control), WBI and WBI/BMR, female mdx host mice. MTT was performed 1 hour after BMR and muscles sampled at 1 hour, 24 hours, 1, 3, 12 and 24 weeks after MTT. Bars indicate s.d. *P<0.05, **P<0.005 (untreated to treated samples) using ANOVA; d and dd indicate significances of P<0.05 or P<0.005, respectively, between treatment groups at each time point using ANOVA (n=6 unless otherwise stated).