Fig. 4. Numbers of donor myoblasts in locally irradiated and contralateral (protected) TA muscles in mdx host mice subjected to local irradiation of one leg. MTT was performed at 1 hour (A) or 1 week (B) after irradiation and muscles sampled at 24 hours, 1 week, 3 weeks, 12 weeks and 24 weeks after MTT. Schematics of the irradiation treatment of host mice (see Fig. 1) are indicated in the top right hand corner. Bars indicate standard deviation. * and ** indicates significance of P<0.05 or P<0.005, respectively, between untreated and treated samples using ANOVA; d and dd indicates significance of P<0.05 or P<0.005, respectively, between treatment groups at each time point using ANOVA, n=6 unless otherwise stated.