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Fig. 3. Cyclins A and B are not degraded in mks1 cells. Paired images of mitotic cells showing tubulin (green), DNA (blue) and cyclin A (red and monochrome; A-D) or cyclin B (red and monochrome; E-H). (A) Wild-type cell in prophase showing cyclin A staining. (B) Wild-type cell at onset of metaphase in which cyclin A has been degraded. (C,D) Metaphase-like mks1 cells in which cyclin A is not degraded. (E) Wild-type cell at metaphase showing cyclin B staining. (F) Wild-type cell at anaphase in which cyclin B has been degraded. (G) Metaphase-like mks1 cells in which cyclin B is not degraded. Scale bar, 10 µm.