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Fig. 1. Endogenous p120 shuttles between the cytoplasm and nucleus in cells lacking E-cadherin expression. Endogenous p120 was localized by immunofluorescence in a panel of E-cadherin-deficient cell lines before (panels A-D) and after (panels E-H) LMB treatment. Treatment with LMB significantly increased nuclear levels of p120, indicating that it is subject to nucleocytoplasmic shuttling.