Fig. 3. Camptothecin and Trail-induced apoptosis is inversely proportional to rate of migration. SF767 and T98G cells were plated onto slides coated with the specified concentration of laminin. Migration was measured 24 hours post seeding (
), cells were then treated with 1 µM camptothecin for 24 hours (SF767) or 100 ng/ml Trail for 16 hours (T98G), stained with DAPI then % apoptotic cells in the rim quantitated as described in Materials and Methods (
). Values represent the mean and standard deviation of three replicate measurements.