Fig. 6. Co-localization of PML and SUMO-1. (A) PML, and SUMO-1 were immunolabeled in control cells (–HS), cells heat shocked for 30 minutes at 43°C (0H), after a recovery period of 4 hours (4H) or immediately following Cd+2 stress (50 µM for 2 hours). PML bodies or PML body remnants are indicated by arrows, and PML-containing microstructures are indicated by arrowheads. (B) All 8 PML bodies in –HS were analyzed. Quantification of these structures is presented in Tables 1 and 2; the bodies, remnants or microstructures described in the tables correspond to the indicated structures, numbered in order from top to bottom in the respective image.