Fig. 5. Roles of dynein in filamentous fungi. (A) Nuclear migration. During the elongation of the hypha by the apical growth (grey arrow), the nuclei migrate towards the growing tip (black arrows) and distribute relatively evenly along the cell length – this migration depends on dynein. Note that the migration distance of each nuclei differs. (B) Organelle transport. In the hyphae, vesicles move in both retrograde (black arrows) and anterograde (blue arrows) directions. It is proposed that dynein drives the retrograde transport of vesicles (blue circles), whereas kinesin drives the anterograde transport (red circles).