Fig. 3. Indirect immunofluorescence keratin staining of gallbladders of K8^+/+ and K8^–/– mice. Gallbladders were removed from age and sex matched K8^+/+ or K8^–/– mice, followed by fixing then staining using the indicated keratin-specific antibodies. L, lumen; scale bar (in a): 10 µm. Note the absence of K8 and the limited compensatory induction of K7 in K8^–/– mouse gallbladder.