Fig. 5. Serologic assessment of liver injury among K8 mouse genotypes after a lithogenic diet. Blood was collected from K8 mice that were fed a lithogenic diet (the same mice as used for the experiments of Table 3), or from five age-matched mice that were fed a normal diet. Sera were isolated and used to measure alkaline phosphatase (AP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT). The y axis shows the mean fold increase in serum enzymes compared with mice fed control diet. ^*P<0.05 when comparing K8^–/– with K8^+/– or K8^+/+.