(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 5. Signalling through integrins: the paxillin/CasL/CrkL pathway. The CasL/CrkL adaptor complex is formed by signalling through {alpha}4ß1, {alpha}4ß7 and LFA-1 on T cells. The figure generalizes the interactions following integrin activation, not all of which have been demonstrated for each T-cell integrin (see text for details).