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Fig. 4. Requirement for microtubules but not dynein for nuclear dynamics in dicentric cdc5-ad rad52 cells. (A-D) Sequential fluorescence images of a dicentic cdc5-ad rad52 cell expressing histone2B-GFP following treatment with benomyl. (E-H) Sequential fluorescence images of two dicentric cdc5-ad dhc1 rad52 cells expressing histone2B-GFP. Note the change in nuclear morphology of the right-hand cell from round with a tail to `dumbbell' (Fig. 4E,F). Also note the growth of filaments from both nuclei, indicated by arrows in Fig. 4G,H. Elapsed time is indicated in seconds. Bar, 5 µm.