JCS -- Sridharan et al. 116 (5): 823 Figure IG3

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Fig. 3. The number of ${alpha}$ SpII ${Sigma}$ * nuclear foci increases with increasing dosage of 8-MOP plus UVA light. Formation of ${alpha}$ SpII ${Sigma}$ * foci in the nuclei of normal human lymphoblastoid cells was examined 15 hours after exposure to varying dosages of 8-MOP plus UVA light. The dosage of 8-MOP plus UVA light was increased by increasing the levels of UVA light at a constant concentration of 8-MOP. Cells stained singly with anti- ${alpha}$ -spectrin were examined. Foci were counted in 100 nuclei at each UVA dose. Nuclei were categorized as having 0-20 foci, 21-40 foci, 41-60 foci, 61-80 foci or 81-100 foci. The y axis indicates the percentage of nuclei in each category. Vertical lines represent s.e.m.