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Fig. 3. Mitotic figures from wild-type and {Delta}p54 mutant larval brains. Aceto-orcein-stained metaphase figures from wild-type (A) and {Delta}p54 (B-F) third instar larval brains. {Delta}p54 mitotic cells frequently show highly condensed chromosomes (B), aneuploid (B,E) or polyploid (D) chromosome sets and circular mitotic figures (C). Characteristically, some cells appear to prematurely separate their sister chromatids (F).