Fig. 1. Correspondence analysis graphs illustrating the dependencies of gene expression profiles during the early cell cycle of CK2 deletion strains. Transcript profiles of -factor-synchronized yeast strains were determined at 0, 7 and 14 minutes after pheromone release by hybridization to oligonucleotide arrays across the whole yeast genome. Expression specificities of single genes can be detected by their distance from the center and the direction of the corresponding condition. (A) ckb1 ckb2 strain compared with the wildtype. (B) cka1 strain compared with the wildtype. (C) cka2 strain compared with the wildtype. Note that CK2 mutants were constructed by gene disruption techniques. Thus, although fractional transcription of deleted CK2 subunit genes results in no functioning proteins, weak transcript signals are detected on oligonucleotide arrays, and their distance from the center is not as far as one might expect.