Fig. 3. Effect of CD concentration on STA- and KT-treated cells. The dependence of cell area on CD concentration was observed for STA or KT-treated cells spreading for 30 minutes (error bars are standard errors of at least 20 measurements). The sigmoidal curve was well fit to the data plotted on the semi-logarithmic scale and yielded the effective half-maximum inhibitory dose (IC₅₀) of CD on STA- and KT-pretreated cells of 3.5 nM and 20 nM, respectively.