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Fig. 6. FHOD1 enhances cell migration. (A) Expression of full-length FHOD1 in WM35 cells enhanced migration to type-I collagen. The migration of control (MSCV) and FHOD1-expressing WM35 cells to type-I collagen (1 µg ml-1 on the left, indicated concentrations on the right) during a 4-5 hour period was measured in a Boyden chamber. (B) Expression of full-length FHOD1 in NIH-3T3 cells enhanced migration to fibronectin, laminin and BCS. Each protein was used at a final concentration of 1 µg ml-1. BCS was added at 10% (v/v). Cells were allowed to migrate for 4-5 hours in a modified Boyden chamber.