Fig. 1. (A) Genomic organization of the coro gene and the sequence of its protein product. Its cytological location is 42C5-D6. coro transcriptional length is 10443 bp, whereas the mRNA is 2610 nucleotides long. The P-element insertion in 409-GAL4 was in the 5' UTR (within the first exon) of CG9446. (B) Northern blot showing a single Coro transcript of
2.5 kb. (C) The predicted protein is 528 amino acids long, with 2 distinct WD40 repeats, shown in red. (D) Predicted coiled coil domain in the C-terminal of Coro protein. Predictions were carried out by submitting the protein sequence to BCM Search Launcher (http://searchlauncher.bcm.tmc.edu/seq-search/struc-predict.html).