Fig. 3. Leg and wing phenotypes displayed by homozygous coro^ex11 flies. (A) Molecular lesions in coro^ex11 and coro^ex6 alleles. coro^ex11 carries a P-element insertion at the 5'UTR. coro^ex6 has a 100 bp deletion in the upstream regulatory region and a translocation within the third exon. (B) Wild-type leg. (C-E) coro^ex11/coro^ex11 legs. Note shortening and thickening of legs (C) and duplication of sex combs (D-E). (F) Wild-type wing blade. (G-H) Wing margin phenotypes seen in coro^ex11/coro^ex11 flies. (G) Both anterior and posterior margins are affected. (H) The anterior margin defect at higher magnification. (I) Wild-type wing blade showing distal most region at higher magnification. (J) coro^ex11/coro^ex11 wing blade. Note thickening of veins, which resembles the Delta phenotype, and small necrotic patches. (K) Adult coro^ex11/coro^ex11 fly showing highly reduced wing blade.