Fig. 6. coro mutant wing discs show defective AP boundary and reduced Dpp signaling to distant cells. (A) Wild-type wing disc. (B) coro^ex11/coro^ex11 wing disc showing separation of anterior and posterior compartments. (B') Higher magnification image of the disc shown in B. (C) coro^ex6/coro^ex6 wing disc. Note that the disc is very small and no specific defect in the AP or DV boundary is seen. (D) coro^ex6/coro^ex11 wing disc. Note both small-disc phenotype as in coro^ex6/coro^ex6 discs and separation of dorsal and ventral compartments along the DV boundary. (E,E'') Optical sections of anti-Arm-stained wild-type wing disc to show that the epithelium is contiguous in all focal planes. (F,F'') Optical sections of anti-Arm-stained coro^ex11/coro^ex11 wing disc to show that peripodial membrane is contiguous and large squamous epithelial cells of the peripodial membrane are normal. Also in the disc proper, the columnar epithelium is contiguous, although mainly at the basal end of the cells. Images in E,E'' and F,F'' were generated by taking nearly 60 optical sections each of 0.5 µm thickness, which were then used to reconstruct disc images at three equal focal planes.