Fig. 7. Down regulation of Dpp signaling in coro mutants. (A,B) Ci expression patterns of wild-type (A) and coro^ex11/coro^ex11 (B) wing discs. Expression of Ci in coro^ex11 wing discs is normal, although they show defective AP boundary (arrows). (C,D) Expression pattern of Dpp in wild-type (C) and coro^ex11/coro^ex11 (D) wing discs. Dpp is visualized with the help of dpp-GAL4/UAS-GFP. In coro^ex11/coro^ex11 wing disc Dpp expression is normal despite separation of anterior and posterior compartments along the AP boundary (arrows). GFP seen in cells outside the AP boundary is mainly because of residual GAL4 activity of coro^ex11. (E,F) Wg expression patterns of wild-type (E) and coro^ex11/coro^ex11 (F) wing discs. Wg expression along the DV boundary is normal in the coro^ex11 wing disc. (G-I) Wild-type (G), coro^ex11/coro^ex11 (H) and coro^ex6/coro^ex6 (I) wing discs stained for Sal expression. Note reduced levels of Sal in coro^ex11 and coro^ex6 discs, particularly in the posterior compartment. Here too we have chosen those coro^ex6 wing discs that show milder phenotype, to examine the effect on Dpp signaling. (J-K) Wild-type (J) and coro^ex11/coro^ex11 (K) wing discs stained for Omb expression. Note that Omb expression in the posterior compartment is nearly absent.