Fig. 6. Diagram illustrating the changes in size and spatial distribution of regions producing the highest traction stress. Colored zones within the keratocyte represent the temporal sequence (blue, yellow, red) in which regions of highest traction stress enlarge, following a calcium transient. The graph shows the duration of each region, with respect to the increase in 90th percentile traction stress (red line), represented by the length of matching colored arrows. The numbered boxes represent different stages of the mechano-chemical feedback cycle as explained in the text.