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Fig. 2. Heparanase localization in cell xenografts and tumor biopsies. (A) PC3 xenograft (a,b), prostate biopsy (c,d) and (B) MCF7 xenograft (a-c) and breast cancer biopsy (d-f) sections were subjected to antigen retrieval and immunostaining with antibody 733. Negative control, in which the primary antibody was omitted, is shown for MCF7 xenograft (Bc) and breast cancer biopsy (Bf). Original magnifications: Aa,c and Ba,d x20; Ab,d and Bb,c,e,f x100.