JCS -- Egberts et al. 117 (11): 2295 Figure IG11

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 11. Ultrastructural changes of the stratum corneum and the transition of stratum granulosum to stratum corneum in CTSD^(–/–) mice. Electron microscopy shows that in wild-type mice (A) the cornified envelope (CE) is clearly visible as dark lines around the corneocytes (arrow). In CTSD^(–/–) mice (B) there is a broadening of the intercellular spaces in the stratum corneum (SC), only a faint staining of the CE (arrow) and the corneocytes are thickened in the axial direction. SG, stratum granulosum.