Fig. 4. (A) MscL subfamily of bacterial MS channels. (B) Phylogenetic tree of MscS homologues. Bacterial MS channels are shown in black, archaeal channels are shown in red, homologues found in fungi and plants are shown in green. The homologues were retrieved from the existing databases (GenBank, Protein DataBank and SwissProt) using BLAST (Altschul et al., 1997) [adapted with permission from Elsevier (Martinac and Kloda, 2003)].