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Fig. 9. HET-s/GFP and HET-s(218-289)/GFP form elongated fibrillar aggregates when expressed with HET-s(157-289). In the prion state, HET-s/GFP and HET-s(218-289)/GFP form dot-like aggregates when expressed alone (left) but fibrillar aggregates when expressed with HET-s(157-289) (right). Notice that dot-like aggregates co-exist with fibrillar aggregates in strains expressing either HET-s/GFP and HET-s(157-289) or HET-s(218-289)/GFP and HET-s(157-289). Scale bar, 4 µm.