Fig. 4. Reversibility of the Lf-effect on the deposition of BM components. Upon withdrawal of Lf at day 10 the deposition of nidogen (A) and BM laminin (C; 1 chain) is largely or partially recovered, whereas continuous treatment (B,D) reveals, at best, only marginal binding to the surface of basal cells. By contrast, there is only little change, at most a moderate reduction in staining for laminin-5 (E,F; 2 chain) and type IV collagen (G,H) between these pairs (control/treated). All shown at day 19. Scale bars: 50 µm.