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Fig. 7. Pharmacological characterisation of spontaneous Ca2+ oscillations in HEK293 cells transfected with RyR3. In A-F, effects of the following drugs or treatments were examined: (A) 10 µM ryanodine; (B) 10-50 µM tetracaine; (C) 20 µM FK506 after transient application of caffeine; (D) 100 µM 2APB; (E) removal of external Ca2+; (F) application of 40 µM SK&F96365.