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Fig. 3. A model for cortical ER inheritance in S. cerevisiae. Myo4p transports ER tubules into the daughter cell along actin cables. She3p functions as an adaptor protein that links Myo4p to the segregating ER tubule. Sec3p stabilizes the cortical association of ER tubules delivered into the bud. The ER tubules are propagated along the bud periphery and form an interconnected tubular network.