Fig. 1. Localization of DP within capillaries was analyzed by immunofluorescence. (A) Dermal capillary (arrows) in rat skin is recognized by antibodies to VE-Cad (green) and DP (red). Arrowheads point to DP staining within desmosomes that are involved in adhering cells within hair follicles including inner and outer root sheath cells. (B) High magnification of area outlined in A shows that DP (red; arrows) is localized directly adjacent to VE-Cad (green; arrowheads). (C) Confocal view of an E9 day mouse yolk sac shows vimentin (green) associated with DP (red; arrows). D-F are cross-sectional, high-magnification views of the yolk sac that show the close association in F of vimentin (green) with DP (red) surrounding the capillary lumen (lu). Nuclei are stained with DAPI in each figure. Bar in A=100 µm; 10 µm in B; 50 µm in C.