Fig. 7. Regulation of resistin mRNA expression in rat testis by the selective ligand of PPAR
, rosiglitazone. (A) A representative RT-PCR assay of the testicular expression levels of resistin mRNA after a 1-week exposure to rosiglitazone (TZD; 5 mg/kg/day), in vivo. (B) A representative RT-PCR assay of testicular expression levels of resistin mRNA after in vitro exposure to 1010-104 M rosiglitazone (TZD). Semi-quantitative values are the mean±s.e.m. of at least four independent determinations. In A, *P<0.05 versus the vehicle-treated (VEH) group; in B, a,b and c denote groups that are statistically different (P<0.01; ANOVA followed by Tukey's test).