Fig. 9. Regulation of in vitro testicular testosterone secretion by resistin. Testicular slices were incubated with increasing doses of resistin-(23-42) (10^–10-10^–6 M) in the absence (–hCG; basal conditions) or the presence (+hCG; stimulated conditions) of 10 IU/ml hCG. The concentration of testosterone in the media was monitored after 90 and 180 minutes incubation; only data from the 90-minute incubation are presented. Values are normalized per gram of incubated tissue. Data are expressed as mean±s.e.m. (n=10-12 samples/group). **P<0.01 vs. corresponding controls (ANOVA followed by Tukey's test).