Fig. 7. Quantification of foci pattern A or B (as shown in Fig. 6A) in human primary cells locally UV irradiated. Normal (A; 198VI), XPA (B; XP456VI) and XPC mutated (C; XP148VI) human primary fibroblasts infected with Adphr-EGFP were locally UV irradiated with 50 J/m². The cells were exposed to dark or PRL treatments immediately after local UV irradiation. These treatments were performed during different periods of time, but up to a maximum period of 2 hours, the samples then being kept in the incubator until analysis by fluorescence microscopy (see bar in legend). The number of cells with foci strongly-fluorescent (pattern A, black bars) or with a less intense fluorescence (pattern B, gray bars) was counted by fluorescence microscopy in different periods of time after local UV irradiation. We counted 100 for each sample, and the data thereby represent the average of three independent experiments.