Fig. 12. Phase-contrast images and outlines of migrating control C3 cells during wound healing. Derived from original video taping, the phase-contrast images (A) of migrating cells starts 2.5 hours after wounding and continues for 12.5 minutes at intervals of 2.5 minutes. (B) The outlines of a representative cell (A, arrow) in which membrane extension zones are filled with red. A single membrane sheet covering nearly the entire leading edge was actively extending and retracting during the 12.5-minute period. Scale bar, 10 µm.