Fig. 8. RACK siRNA decreases tyrosinase activity. (A) A paired culture of melanocytes were transfected with 10nM control RNA or RACK-I siRNA. 72 hours later, cells were harvested and immunoblot analysis was performed for RACK-I, tyrosinase and PKC-ß. (B) In parallel, tyrosinase activity was measured. Statistical analysis was performed using a paired Student t-test.