Fig. 1. Myosin inhibitors affect cell shape and stress fiber organization. Asynchronous cultures of myoblasts were treated for 24 hours with low serum medium alone (a), or in the presence of DMSO (b), 30 mM BDM (c) or 15 µM ML7 (d). Actin stress fibers (Oregon Green-phalloidin) and cell spreading are markedly reduced in drug-treated cells. Scale bar: 20 µm.