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Fig. 1. Effect of TSA on the cell cycle as analyzed by FACS. Black bars, control cells; dark gray bars, cells treated with 50 ng/ml TSA; light gray bars, cells treated with 100 ng/ml TSA. The overall changes in the distribution after (A) 12 hours and (C) 24 hours, and the change weighted with the fraction of cells in the given cell cycle stage after (B) 12 hours and (D) 24 hours are shown.