Fig. 2. Transepithelial resistance in human airway epithelia expressing CAR, CAR^GSIV, or GFP. Primary human airway epithelia were infected with adenoviruses expressing CAR, CAR^GSIV, or eGFP and transepithelial resistance was measured 3 days after infection (n=12). CAR^GSIV failed to increase the transepithelial resistance to the same degree as wild-type CAR. Mean resistances differ significantly from each other (*P<0.002). Cultures infected with Ad-eGFP did not differ significantly from baseline transepithelial resistance.