Fig. 7. The ratio of the numbers of moving vesicles vs. total vesicles after drug treatments, overexpression of GFP-tagged dominant-negative kinesin (GFP-DNKHC) and antisense oligonucleotide treatment against kinesin. ER vesicles were labeled with RFP-KDEL. The proportion of moving vesicles was significantly decreased by nocodazole treatment (10 µg/ml), but not by latrunculin A treatment (1 µg/ml). Overexpression of GFP-DNKHC and antisense oligonucleotide treatment against kinesin also decreased the proportion of the moving vesicles. Numbers in parentheses indicate the number of neurons examined.