Fig. 6. PI3K activity affects PGC morphology and filopodia stability. (A) The outline of 8 control PGCs and (B) 8 PGCs expressing dnPI3K. The outlines of PGCs were generated as described in the Materials and Methods. Expression of dnPI3K in PGCs reduces filopodia stability and length (D; Movie S7 in supplementary material), as compared with control embryos (C; Movie S6 in supplementary material). Arrows in C and D indicate filopodia. The area demarcated in red is enlarged in the right panels.