Fig. 11. Diagrams of F-actin localization in (A) control and (B) mhcA- or 3XASP and (C) 3XALA cells in buffer and in response to the increasing temporal wave of cAMP in the front of a wave. (D) Model of the regulation of F-actin localization in the cytoplasm and cortex in response to the increasing gradient of cAMP in the front of a wave.