Fig. 3. Localization of Rad18Sc protein in mouse and human testis. (A-C) Sections of wild-type mouse testis were stained with anti-Rad18Sc. (A,B) A positive signal was found in spermatogonia (sgo), primary spermatocytes (scy) and round spermatids (rst). (C) Hardly any Rad18Sc was present in elongating spermatids (est). In primary spermatocytes, the highest amount of Rad18Sc was found associated with the XY body (circles). (D) In cross-sections of human testis, anti-Rad18Sc gave marked staining of the XY body (circles) in primary spermatocytes (scy). Bar, 30 µm.