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Fig. 7. Rad18Sc protein localizes to unsynapsed regions of the 113 bivalent. The morphology of the 113 bivalent was classified as partially synapsed A shape (PA, intermediate degree of synapsis), partially synapsed horsheshoe shape (PH, almost complete synapsis), partially synapsed rest (PR, low degree of synapsis), and completely synapsed (CS). The accumulation of Rad18Sc to these regions was analyzed by immunostaining (upper panel). Over groups, the number of nuclei positive for Rad18Sc was found to be increased when synapsis of these bivalents was less complete (lower panel). The arrowhead indicates the 113 bivalent.